在这项工作中，我们考虑了对具有非负LEBESGUE密度的概率度量的预期估计，并且是最新的正常化常数。我们专注于通过失业不足的Langevin Dynamics开发一种无偏见的方法，由于统计和机器学习的应用，事实证明，该动态已被证明很受欢迎。特别是连续时间，可以构建动力学以承认感兴趣的概率作为固定度量。我们基于双随机估计而开发了一种新颖的方案，该方案仅需要访问动力学的时间限制版本，并且是实用算法中使用的动力学版本。我们证明，根据标准假设，我们的估计器具有有限的差异，并且具有有限的预期成本，或者具有有限的成本具有很高的可能性。为了说明我们的理论发现，我们提供了验证我们理论的数值实验，其中包括贝叶斯统计和统计物理学的挑战示例。

在本文中，我们考虑了贝叶斯（DNNS），尤其是Trace-Class神经网络（TNN）先验，贝叶斯的推论是Sell等人提出的。 [39]。在推理问题的背景下，这种先验是对经典体系结构的更强大替代品。对于这项工作，我们为此类模型开发了多级蒙特卡洛（MLMC）方法。 MLMC是一种流行的差异技术，在贝叶斯统计和不确定性定量中具有特殊应用。我们展示了在[4]中引入的特定高级MLMC方法如何应用于DNN的贝叶斯推断并从数学上确定，即实现特定平方误差的计算成本，与后验预期相关，可以通过几个减少订单，与更常规的技术。为了验证此类结果，我们提供了许多关于机器学习中产生的模型问题的数值实验。其中包括贝叶斯回归，以及贝叶斯分类和增强学习。

Applying Machine learning to domains like Earth Sciences is impeded by the lack of labeled data, despite a large corpus of raw data available in such domains. For instance, training a wildfire classifier on satellite imagery requires curating a massive and diverse dataset, which is an expensive and time-consuming process that can span from weeks to months. Searching for relevant examples in over 40 petabytes of unlabelled data requires researchers to manually hunt for such images, much like finding a needle in a haystack. We present a no-code end-to-end pipeline, Curator, which dramatically minimizes the time taken to curate an exhaustive labeled dataset. Curator is able to search massive amounts of unlabelled data by combining self-supervision, scalable nearest neighbor search, and active learning to learn and differentiate image representations. The pipeline can also be readily applied to solve problems across different domains. Overall, the pipeline makes it practical for researchers to go from just one reference image to a comprehensive dataset in a diminutive span of time.

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge typically rely on automated evaluations on limited benchmarks. There is no standard to evaluate model predictions and reasoning across a breadth of tasks. To address this, we present MultiMedQA, a benchmark combining six existing open question answering datasets spanning professional medical exams, research, and consumer queries; and HealthSearchQA, a new free-response dataset of medical questions searched online. We propose a framework for human evaluation of model answers along multiple axes including factuality, precision, possible harm, and bias. In addition, we evaluate PaLM (a 540-billion parameter LLM) and its instruction-tuned variant, Flan-PaLM, on MultiMedQA. Using a combination of prompting strategies, Flan-PaLM achieves state-of-the-art accuracy on every MultiMedQA multiple-choice dataset (MedQA, MedMCQA, PubMedQA, MMLU clinical topics), including 67.6% accuracy on MedQA (US Medical License Exam questions), surpassing prior state-of-the-art by over 17%. However, human evaluation reveals key gaps in Flan-PaLM responses. To resolve this we introduce instruction prompt tuning, a parameter-efficient approach for aligning LLMs to new domains using a few exemplars. The resulting model, Med-PaLM, performs encouragingly, but remains inferior to clinicians. We show that comprehension, recall of knowledge, and medical reasoning improve with model scale and instruction prompt tuning, suggesting the potential utility of LLMs in medicine. Our human evaluations reveal important limitations of today's models, reinforcing the importance of both evaluation frameworks and method development in creating safe, helpful LLM models for clinical applications.

Authorship style transfer involves altering the style of text to match the style of some target author whilst preserving the semantic meaning of the original text. Existing approaches to unsupervised authorship style transfer like STRAP have largely focused on style transfer for target authors with many examples of their writing style through books, speeches, or other published works (Krishna et al., 2020). Due to this high-resource training data requirement (often greater than 100,000 words), these approaches are often only useful for style transfer to the style of published authors, politicians, or other well-known figures and authorship styles. In this paper, we attempt to perform low-resource authorship style transfer, a more challenging class of authorship style transfer where only a limited amount of text in the target author's style may exist. In our experiments, we specifically choose source and target authors from Reddit to perform style transfer over their Reddit posts, limiting ourselves to just 16 posts (on average $\approx$ 500 words) of the target author's style. We then propose a method for automatic evaluation on the low-resource authorship style transfer task utilizing authorship and style representation embeddings (Rivera-Soto et al., 2021; Wegmann et al., 2022). We evaluate our style transferred outputs with the proposed automatic evaluation method and find that our method, STYLL, is able to outperform STRAP and a comprehensive set of baselines.

As Artificial and Robotic Systems are increasingly deployed and relied upon for real-world applications, it is important that they exhibit the ability to continually learn and adapt in dynamically-changing environments, becoming Lifelong Learning Machines. Continual/lifelong learning (LL) involves minimizing catastrophic forgetting of old tasks while maximizing a model's capability to learn new tasks. This paper addresses the challenging lifelong reinforcement learning (L2RL) setting. Pushing the state-of-the-art forward in L2RL and making L2RL useful for practical applications requires more than developing individual L2RL algorithms; it requires making progress at the systems-level, especially research into the non-trivial problem of how to integrate multiple L2RL algorithms into a common framework. In this paper, we introduce the Lifelong Reinforcement Learning Components Framework (L2RLCF), which standardizes L2RL systems and assimilates different continual learning components (each addressing different aspects of the lifelong learning problem) into a unified system. As an instantiation of L2RLCF, we develop a standard API allowing easy integration of novel lifelong learning components. We describe a case study that demonstrates how multiple independently-developed LL components can be integrated into a single realized system. We also introduce an evaluation environment in order to measure the effect of combining various system components. Our evaluation environment employs different LL scenarios (sequences of tasks) consisting of Starcraft-2 minigames and allows for the fair, comprehensive, and quantitative comparison of different combinations of components within a challenging common evaluation environment.

Knowledge graph (KG) is used to represent data in terms of entities and structural relations between the entities. This representation can be used to solve complex problems such as recommendation systems and question answering. In this study, a set of candidate drugs for COVID-19 are proposed by using Drug repurposing knowledge graph (DRKG). DRKG is a biological knowledge graph constructed using a vast amount of open source biomedical knowledge to understand the mechanism of compounds and the related biological functions. Node and relation embeddings are learned using knowledge graph embedding models and neural network and attention related models. Different models are used to get the node embedding by changing the objective of the model. These embeddings are later used to predict if a candidate drug is effective to treat a disease or how likely it is for a drug to bind to a protein associated to a disease which can be modelled as a link prediction task between two nodes. RESCAL performed the best on the test dataset in terms of MR, MRR and Hits@3.

Deep neural networks (DNNs) have rapidly become a \textit{de facto} choice for medical image understanding tasks. However, DNNs are notoriously fragile to the class imbalance in image classification. We further point out that such imbalance fragility can be amplified when it comes to more sophisticated tasks such as pathology localization, as imbalances in such problems can have highly complex and often implicit forms of presence. For example, different pathology can have different sizes or colors (w.r.t.the background), different underlying demographic distributions, and in general different difficulty levels to recognize, even in a meticulously curated balanced distribution of training data. In this paper, we propose to use pruning to automatically and adaptively identify \textit{hard-to-learn} (HTL) training samples, and improve pathology localization by attending them explicitly, during training in \textit{supervised, semi-supervised, and weakly-supervised} settings. Our main inspiration is drawn from the recent finding that deep classification models have difficult-to-memorize samples and those may be effectively exposed through network pruning \cite{hooker2019compressed} - and we extend such observation beyond classification for the first time. We also present an interesting demographic analysis which illustrates HTLs ability to capture complex demographic imbalances. Our extensive experiments on the Skin Lesion Localization task in multiple training settings by paying additional attention to HTLs show significant improvement of localization performance by $\sim$2-3\%.

When developing deep learning models, we usually decide what task we want to solve then search for a model that generalizes well on the task. An intriguing question would be: what if, instead of fixing the task and searching in the model space, we fix the model and search in the task space? Can we find tasks that the model generalizes on? How do they look, or do they indicate anything? These are the questions we address in this paper. We propose a task discovery framework that automatically finds examples of such tasks via optimizing a generalization-based quantity called agreement score. We demonstrate that one set of images can give rise to many tasks on which neural networks generalize well. These tasks are a reflection of the inductive biases of the learning framework and the statistical patterns present in the data, thus they can make a useful tool for analysing the neural networks and their biases. As an example, we show that the discovered tasks can be used to automatically create adversarial train-test splits which make a model fail at test time, without changing the pixels or labels, but by only selecting how the datapoints should be split between the train and test sets. We end with a discussion on human-interpretability of the discovered tasks.

Recent improvements in conditional generative modeling have made it possible to generate high-quality images from language descriptions alone. We investigate whether these methods can directly address the problem of sequential decision-making. We view decision-making not through the lens of reinforcement learning (RL), but rather through conditional generative modeling. To our surprise, we find that our formulation leads to policies that can outperform existing offline RL approaches across standard benchmarks. By modeling a policy as a return-conditional diffusion model, we illustrate how we may circumvent the need for dynamic programming and subsequently eliminate many of the complexities that come with traditional offline RL. We further demonstrate the advantages of modeling policies as conditional diffusion models by considering two other conditioning variables: constraints and skills. Conditioning on a single constraint or skill during training leads to behaviors at test-time that can satisfy several constraints together or demonstrate a composition of skills. Our results illustrate that conditional generative modeling is a powerful tool for decision-making.